Two sample MR report
NAGK_Monocyte (Mono) against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | 0.0591215 | 0.1176514 | 0.6366510 |
| Weighted median | 7 | 0.0393236 | 0.0164189 | 0.0166194 |
| Inverse variance weighted | 7 | 0.0277575 | 0.0140452 | 0.0481207 |
| Simple mode | 7 | 0.0410316 | 0.0220909 | 0.1126297 |
| Weighted mode | 7 | 0.0388470 | 0.0190317 | 0.0873025 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 7.538645 | 5 | 0.1835618 |
| Inverse variance weighted | 7.647632 | 6 | 0.2650716 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0153797 | 0.0572034 | 0.7987783 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 5.85e-05 | 0 | TRUE | 0.4690284 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
